Genome Editing

Genome editing or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified, or replaced in the genome of a living organism.

Gene Knockdown:

Gene knockdown is the reduction of gene expression in an organism. It can either happen by chemical agents or genetic modification. Gene knockdown can be complete or partial, offering flexibility in studying the gene’s role in the biology of the organism. We are here if your cell experiment needs gene silencing or inactive messenger RNA for a specific gene.

Gene Overexpression:

The overexpression of proteins is critical for many applications, including studying the function of the gene, and in functional assays and screens. Please ask for a consultation if you need to downstream analysis for your cell culture in vitro

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Transformation:

Selective transduction of only target cells and tissues represents a major goal of therapeutic gene delivery. Lentivirus (LV) is one of the most efficient gene transduction systems for stable, long-term transgene expression among common viral vectors. Unfortunately, gene delivery to your target cells using a lentiviral vector is tricky and biohazardous. If you don’t have an efficient method of gene transfer using lentiviral, you can spend time over six months or more. Contact us if you need to transform your targeted cells or tissues using a lentiviral vector since we have a highly efficient and safe method.

Gene Expression Analysis:

Genome-wide and targeted at specific gene subsets, it has played a vital role in understanding stem cells’ genetic attributes by identifying molecular signatures that characterize cell function. Gene expression is highly recommended when verifying cell purity, heterogeneity, and functional activity. We can extract RNA and run and analyze samples to determine mRNA levels (specific genes of your interest) using qPCR.

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if you need a specific gene delivery or analysis for the project, but it is not listed here Contact Us.